Crespo_1996_Neurosci.Lett_205_149

Using double-staining techniques, the distribution of NADPH-diaphorase (ND)- and nitric oxide synthase (NOS)-positive cells was compared in the periglomerular region of typical and atypical rat olfactory glomeruli. Dorsomedial and ventrolateral atypical glomeruli contained similar number of ND/NOS-positive periglomerular cells. The number of ND/NOS-stained periglomerular cells was much higher (P < 0.001) in typical than in atypical glomeruli. The present results indicate that, in addition to described neurochemical and ultrastructural differences between the neuropile of typical and atypical glomeruli, there are also marked differences in the phenotype of periglomerular interneurons of both glomerular subsets.