| Title : Biphasic regulation of detergent-solubilized muscarinic acetylcholine receptors from rat cerebral cortex by N-ethylmaleimide - Dennison_1985_Res.Commun.Chem.Pathol.Pharmacol_47_465 |
| Author(s) : Dennison RL, Jr. , Wenger DA , Aronstam RS |
| Ref : Res Commun Chem Pathol Pharmacol , 47 :465 , 1985 |
|
Abstract :
Muscarinic acetylcholine receptors were solubilized from rat cerebral cortex with 1% digitonin. Treatment with N-ethylmaleimide decreased or increased agonist affinity for the receptor, depending on the extent of alkylation. This indicates that certain determinants of receptor state do not depend on interactions with other membrane structures. |
| PubMedSearch : Dennison_1985_Res.Commun.Chem.Pathol.Pharmacol_47_465 |
| PubMedID: 3992023 |
Dennison RL, Jr., Wenger DA, Aronstam RS (1985)
Biphasic regulation of detergent-solubilized muscarinic acetylcholine receptors from rat cerebral cortex by N-ethylmaleimide
Res Commun Chem Pathol Pharmacol
47 :465
Dennison RL, Jr., Wenger DA, Aronstam RS (1985)
Res Commun Chem Pathol Pharmacol
47 :465