| Title : Thyroglobulin complementary DNA as a means to investigate congenital goiters with impaired thyroglobulin synthesis - Dinsart_1978_Ann.Endocrinol.(Paris)_39_133 |
| Author(s) : Dinsart C , Wagar G , Van Voorthuizen F , Vassart G |
| Ref : Ann Endocrinol (Paris) , 39 :133 , 1978 |
|
Abstract :
A congenital goiter with impaired thyroglobulin synthesis has been investigated for the presence of messenger RNA coding for thyroglobulin. Using complementary DNA to beef 33 S thyroglobulin mRNA as a probe, we have found that thyroglobulin related sequences are present in the goiter but at a concentration lower than in normal human thyroids. We conclude that the disease is not due to a complete deletion of thyroglobulin gene. |
| PubMedSearch : Dinsart_1978_Ann.Endocrinol.(Paris)_39_133 |
| PubMedID: 686650 |
Dinsart C, Wagar G, Van Voorthuizen F, Vassart G (1978)
Thyroglobulin complementary DNA as a means to investigate congenital goiters with impaired thyroglobulin synthesis
Ann Endocrinol (Paris)
39 :133
Dinsart C, Wagar G, Van Voorthuizen F, Vassart G (1978)
Ann Endocrinol (Paris)
39 :133