Dishovski_1981_Eksp.Med.Morfol_20_62

Reference

Title : [Effect of the organophosphorus compound neguvon on the dopamine content in the rat brain]. [Bulgarian] - Dishovski_1981_Eksp.Med.Morfol_20_62
Author(s) : Dishovski K , Panova I , Uzunov P
Ref : Eksperimentalna Meditsina i Morfologiia , 20 :62 , 1981
Abstract :

The authors found that the phosphororganic pesticide neguvon in a dose of 200 mg/kg of body weight diminished the content of dopamine in the striatum of white rats. This effect was increased after daily administration of the same dose for a period of 5 days. The reactivator of cholinesterase TMB-4(Trimedoxime) and H-choline blocker tropacine prevented this effect. They discussed the connection between the changes in the content of dopamine and modulating role of presynaptic choline receptors of H- and M- types in the dopaminergic terminals of the striatum.

PubMedSearch : Dishovski_1981_Eksp.Med.Morfol_20_62
PubMedID: 7250022

Related information

Inhibitor Trichlorfon~Metrifonate
Reactivator Trimedoxime

Citations formats

Dishovski K, Panova I, Uzunov P (1981)
[Effect of the organophosphorus compound neguvon on the dopamine content in the rat brain]. [Bulgarian]
Eksperimentalna Meditsina i Morfologiia 20 :62

Dishovski K, Panova I, Uzunov P (1981)
Eksperimentalna Meditsina i Morfologiia 20 :62