| Title : The role of the cytoskeleton in neuromuscular junction formation - Dobbins_2006_J.Mol.Neurosci_30_115 |
| Author(s) : Dobbins GC , Zhang B , Xiong WC , Mei L |
| Ref : Journal of Molecular Neuroscience , 30 :115 , 2006 |
|
Abstract :
The cytoskeleton plays a vital role in neuromuscular junction (NMJ) formation. It is responsible for shaping synaptic membrane into folds opposed to presynaptic active zones and anchoring acetylcholine receptors (AChRs) to the crest of the junctional folds. Acetylcholine receptors (AChRs) associate with the actin cytoskeleton, the disruption of which affects spontaneous and agrin-induced AChR clusters (Prives et al., 1982; Connolly, 1984; Peng and Phelan, 1984; Bloch, 1986; Dai et al., 2000). How AChRs are tethered to the actin cytoskeleton remains unclear. |
| PubMedSearch : Dobbins_2006_J.Mol.Neurosci_30_115 |
| PubMedID: 17192654 |
Dobbins GC, Zhang B, Xiong WC, Mei L (2006)
The role of the cytoskeleton in neuromuscular junction formation
Journal of Molecular Neuroscience
30 :115
Dobbins GC, Zhang B, Xiong WC, Mei L (2006)
Journal of Molecular Neuroscience
30 :115