| Title : Iontronic Photoelectrochemical Biorecognition Probing - Dong_2024_ACS.Sens__ |
| Author(s) : Dong H , Wang HY , Xu YT , Zhang X , Chen HY , Xu JJ , Zhao WW |
| Ref : ACS Sens , : , 2024 |
| Abstract : Herein, the first iontronic photoelectrochemical (PEC) biorecognition probing is devised by rational engineering of a dual-functional bioconjugate, i.e., a light-sensitive intercalated structural DNA, as a smart gating module confined within a nanotip, which could respond to both the incident light and biotargets of interest. Light stimulation of the bioconjugate could intensify the negative charge at the nano-orifice to sustain enhanced ionic current. The presence of proteins (e.g., acetylcholinesterase, AChE) or nucleic acids (e.g., microRNA (miR)-10b) could lead to bioconjugate release with altered ionic signaling. The practical applicability of the methodology is confirmed by AChE detection in human serum and miR-10b detection in single cells. |
| ESTHER : Dong_2024_ACS.Sens__ |
| PubMedSearch : Dong_2024_ACS.Sens__ |
| PubMedID: 38258286 |
Dong H, Wang HY, Xu YT, Zhang X, Chen HY, Xu JJ, Zhao WW (2024)
Iontronic Photoelectrochemical Biorecognition Probing
ACS Sens
:
Dong H, Wang HY, Xu YT, Zhang X, Chen HY, Xu JJ, Zhao WW (2024)
ACS Sens
: