| Title : The effect of receptor desensitization on the action of alpha-bungaro-toxin on cultured skeletal muscle - Dryden_1974_Br.J.Pharmacol_51_456 |
| Author(s) : Dryden WF , Harvey AL |
| Ref : British Journal of Pharmacology , 51 :456 , 1974 |
|
Abstract :
The effect of receptor desensitization produced by carbachol on the antagonist action of alpha-bungarotoxin has been studied in cultured skeletal muscle from chick embryos. In control preparations, alpha-bungarotoxin irreversibly blocked depolarization produced by carbachol. However, after receptor desensitization, alpha-bungarotoxin was no longer effective in blocking the response to carbachol. It is concluded that desensitization protects cholinoceptors from the action of alpha-bungarotoxin. |
| PubMedSearch : Dryden_1974_Br.J.Pharmacol_51_456 |
| PubMedID: 4476225 |
Dryden WF, Harvey AL (1974)
The effect of receptor desensitization on the action of alpha-bungaro-toxin on cultured skeletal muscle
British Journal of Pharmacology
51 :456
Dryden WF, Harvey AL (1974)
British Journal of Pharmacology
51 :456