Durand_2021_J.Exp.Biol__

Reference

Title : Neuroligin 1 expression is linked to plasticity of behavioral and neuronal responses to sex pheromone in the male moth Agrotis ipsilon - Durand_2021_J.Exp.Biol__
Author(s) : Durand N , Aguilar P , Demondion E , Bourgeois T , Bozzolan F , Debernard S
Ref : J Exp Biol , : , 2021
Abstract :

In the moth Agrotis ipsilon, the behavioral response of males to the female-emitted sex pheromone increases throughout adult life and following a prior exposure to sex pheromone whereas it is temporally inhibited after the onset of mating. This behavioral flexibility is paralleled with changes in neuronal sensitivity to pheromone signal within the primary olfactory centers, the antennal lobes. In the present study, we tested the hypothesis that neuroligins, postsynaptic transmembrane proteins known to act as mediators of neuronal remodeling, are involved in the olfactory modulation in A. ipsilon males. We cloned a full-length cDNA encoding neuroligin 1 which is expressed predominantly in brain and especially in antennal lobes. The level of neuroligin 1 expression in antennal lobes gradually raised from day-2 until day-4 of adult life as well as at 24 h, 48 h and 72 h following pre-exposure to sex pheromone and the temporal dynamic of these changes correlated with increased sex pheromone responsiveness. By contrast, there was no significant variation in antennal lobe neuroligin 1 expression during the post-mating refractory period. Taken together, these results highlighted that age- and odor experience-related increase in sex pheromone responsiveness is linked to the overexpression of neuroligin 1 in antennal lobes, thus suggesting a potential role played by this postsynaptic cell-adhesion molecule in mediating the plasticity of central olfactory system in A. ipsilon.

PubMedSearch : Durand_2021_J.Exp.Biol__
PubMedID: 34647597

Related information

Citations formats

Durand N, Aguilar P, Demondion E, Bourgeois T, Bozzolan F, Debernard S (2021)
Neuroligin 1 expression is linked to plasticity of behavioral and neuronal responses to sex pheromone in the male moth Agrotis ipsilon
J Exp Biol :

Durand N, Aguilar P, Demondion E, Bourgeois T, Bozzolan F, Debernard S (2021)
J Exp Biol :