Egea_1987_Cell.Tissue.Res_248_207

Reference

Title : Structural changes at pure cholinergic synaptosomes during the transmitter release induced by A-23187 in Torpedo marmorata. A freeze-fracture study - Egea_1987_Cell.Tissue.Res_248_207
Author(s) : Egea G , Esquerda JE , Calvet R , Solsona C , Marsal J
Ref : Cell Tissue Research , 248 :207 , 1987
Abstract :

Pure cholinergic synaptosomes isolated from the electric organ of Torpedo marmorata were stimulated by calcium ionophore A-23187. The effect of time course of stimulation on the changes in intramembrane particles (IMPs) on presynaptic membranes was studied by quick-freezing and aldehyde-fixation freeze-fracture. We showed that the decrease of small-particle density at the P-face and the increase of large-particle density at the E-face was maximum after 30 sec of A-23187 stimulation. Later, the density of synaptic vesicles decreased. We suggest that the redistribution of IMPs on the presynaptic membrane and acetylcholine (ACh) release from pure cholinergic synaptosomes have a similar time course when triggered by A-23187.

PubMedSearch : Egea_1987_Cell.Tissue.Res_248_207
PubMedID: 3105889

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Citations formats

Egea G, Esquerda JE, Calvet R, Solsona C, Marsal J (1987)
Structural changes at pure cholinergic synaptosomes during the transmitter release induced by A-23187 in Torpedo marmorata. A freeze-fracture study
Cell Tissue Research 248 :207

Egea G, Esquerda JE, Calvet R, Solsona C, Marsal J (1987)
Cell Tissue Research 248 :207