Title : Adherence and motility characteristics of clinical Acinetobacter baumannii isolates - Eijkelkamp_2011_FEMS.Microbiol.Lett_323_44 |
Author(s) : Eijkelkamp BA , Stroeher UH , Hassan KA , Papadimitrious MS , Paulsen IT , Brown MH |
Ref : FEMS Microbiology Letters , 323 :44 , 2011 |
Abstract :
Acinetobacter baumannii continues to be a major health problem especially in hospital settings. Herein, features that may play a role in persistence and disease potential were investigated in a collection of clinical A. baumannii strains from Australia. Twitching motility was found to be a common trait in A. baumannii international clone I strains and in abundant biofilm formers, whereas swarming motility was only observed in isolates not classified within the international clone lineages. Bioinformatic analysis of the type IV fimbriae revealed a correlation between PilA sequence homology and motility. A high level of variability in adherence to both abiotic surfaces and epithelial cells was found. We report for the first time the motility characteristics of a large number of A. baumannii isolates and present a direct comparison of A. baumannii binding to nasopharyngeal and lung epithelial cells. |
PubMedSearch : Eijkelkamp_2011_FEMS.Microbiol.Lett_323_44 |
PubMedID: 22092679 |
Gene_locus related to this paper: aciba-f5iht4 , aciba-a0a009wzt4 |
Gene_locus | aciba-f5iht4 aciba-a0a009wzt4 |
Eijkelkamp BA, Stroeher UH, Hassan KA, Papadimitrious MS, Paulsen IT, Brown MH (2011)
Adherence and motility characteristics of clinical Acinetobacter baumannii isolates
FEMS Microbiology Letters
323 :44
Eijkelkamp BA, Stroeher UH, Hassan KA, Papadimitrious MS, Paulsen IT, Brown MH (2011)
FEMS Microbiology Letters
323 :44