| Title : [Pharmacokinetics of dipyroxime in the body of rats and dogs]. [Russian] - Elaeva_1987_Farmakol.Toksikol_50_85 |
| Author(s) : Elaeva NL , Kul'bitskii GN , Predtechenskii MB |
| Ref : Farmakologiia i Toksikologiia , 50 :85 , 1987 |
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Abstract :
Pharmacokinetics of dipyroxime was studied following intravenous injection to noninbred albino male rats. Dipyroxime is a cholinesterase reactivating drug now widely used as an antidote in poisonings caused by organophosphorus pesticides. Dipyroxime pharmacokinetics analysis made it possible to propose a formula for approximation of the data on another animal species (dogs). The drug concentration in the dog blood plasma is in a good correlation with the predicted level. |
| PubMedSearch : Elaeva_1987_Farmakol.Toksikol_50_85 |
| PubMedID: 3582640 |
Elaeva NL, Kul'bitskii GN, Predtechenskii MB (1987)
[Pharmacokinetics of dipyroxime in the body of rats and dogs]. [Russian]
Farmakologiia i Toksikologiia
50 :85
Elaeva NL, Kul'bitskii GN, Predtechenskii MB (1987)
Farmakologiia i Toksikologiia
50 :85