Elinder_1989_Eur.J.Pharmacol_164_599

Reference

Title : Effects of THA on ionic currents in myelinated axons of Xenopus laevis - Elinder_1989_Eur.J.Pharmacol_164_599
Author(s) : Elinder F , Mohammed AK , Winblad B , Arhem P
Ref : European Journal of Pharmacology , 164 :599 , 1989
Abstract :

In voltage-clamp experiments with the myelinated nerve fibre of Xenopus laevis, 9-amino-1,2,3,4-tetrahydroacridine (THA) decreased both Na+ and K+ currents and shifted the steady state inactivation potential curve in a negative direction. The effects may be described as (a) a decrease of the permeability constant PNa, (b) a modified potential dependence of the inactivating system and (c) a decrease of PK. The Na+ system was affected more than the K+ system.

PubMedSearch : Elinder_1989_Eur.J.Pharmacol_164_599
PubMedID: 2475350

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Citations formats

Elinder F, Mohammed AK, Winblad B, Arhem P (1989)
Effects of THA on ionic currents in myelinated axons of Xenopus laevis
European Journal of Pharmacology 164 :599

Elinder F, Mohammed AK, Winblad B, Arhem P (1989)
European Journal of Pharmacology 164 :599