Elyasi_2025_Clin.Case.Rep_13_e71206

A diagnosis of neuroleptic malignant syndrome (NMS) was made in a 96-year-old man, representing the oldest documented case in the existing medical literature. Even at very low doses of antipsychotic medications, older adults are more likely to develop NMS. This increased susceptibility may exacerbate other risk factors, such as preexisting neurological disorders or the concurrent use of cholinesterase inhibitors.