| Title : Radioreceptor assay for oxyphenonium - Ensing_1984_Eur.J.Respir.Dis.Suppl_135_143 |
| Author(s) : Ensing K , de Zeeuw RA |
| Ref : Eur J Respir Dis Suppl , 135 :143 , 1984 |
|
Abstract :
The development of a radioreceptor assay for the quaternary anticholinergic drug, oxyphenonium, in plasma is reported. It is based on competition between this drug and 3H-dexetimide for binding to muscarinic receptors. After ion pair extraction and reextraction, the drug can be determined in plasma at concentrations down to a value of 100 pg/ml. This permits pharmacokinetic studies to be made after inhalation of oxyphenonium. |
| PubMedSearch : Ensing_1984_Eur.J.Respir.Dis.Suppl_135_143 |
| PubMedID: 6428927 |
Ensing K, de Zeeuw RA (1984)
Radioreceptor assay for oxyphenonium
Eur J Respir Dis Suppl
135 :143
Ensing K, de Zeeuw RA (1984)
Eur J Respir Dis Suppl
135 :143