Title : Ciliary muscle choline acetyltransferase and acetylcholinesterase after ciliary ganglionectomy - Erickson-Lamy_1990_Exp.Eye.Res_51_295 |
Author(s) : Erickson-Lamy KA , Johnson CD , True-Gabelt B , Kaufman PL |
Ref : Experimental Eye Research , 51 :295 , 1990 |
Abstract :
Choline acetyltransferase (ChAT; EC 2.3.1.6) and acetylcholinesterase (AChE; EC 3.1.1.7) activities were measured in cynomolgus monkey ciliary muscle 1 month and 6 or more months after ciliary ganglionectomy (CG) or post-ganglionic ciliary neurectomy (PCN). ChAT activity was undetectable and AChE activity was elevated 1 month after CG or PCN, while both averaged about 30% of normal levels 6 or more months after denervation. Four out of six eyes reinnervated by functional criteria 6-12 months after CG or PCN. In one of the two remaining eyes permanently denervated, ChAT was absent from the ciliary muscle. In the other, ChAT activity was about 50% of normal, similar to the reinnervated eyes, but the regenerated cholinergic nerves were not approximated to the ciliary muscle fibers. |
PubMedSearch : Erickson-Lamy_1990_Exp.Eye.Res_51_295 |
PubMedID: 2401348 |
Erickson-Lamy KA, Johnson CD, True-Gabelt B, Kaufman PL (1990)
Ciliary muscle choline acetyltransferase and acetylcholinesterase after ciliary ganglionectomy
Experimental Eye Research
51 :295
Erickson-Lamy KA, Johnson CD, True-Gabelt B, Kaufman PL (1990)
Experimental Eye Research
51 :295