| Title : One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM - Fu_2020_Bioorg.Chem_99_103888 |
| Author(s) : Fu Y , Lu Z , Ma X , Fang K , He X , Xu H , Hu Y |
| Ref : Bioorg Chem , 99 :103888 , 2020 |
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Abstract :
Lipase TLIM was reported to be an efficient, commercially available and reusable catalyst for the Knoevenagel-Michael cascade reactions of aldehydes, malononitrile/ethyl cyanoacetate and 4-hydroxycoumarin/1, 3-cyclohexanedione/dimedone in aqueous DMSO. This methodology presents many superiorities such as simple procedure, mild reaction conditions, commercially available and reusable catalyst, high substrate applicability, the ability to be scaled up, and good to excellent yields. |
| PubMedSearch : Fu_2020_Bioorg.Chem_99_103888 |
| PubMedID: 32388204 |
Fu Y, Lu Z, Ma X, Fang K, He X, Xu H, Hu Y (2020)
One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM
Bioorg Chem
99 :103888
Fu Y, Lu Z, Ma X, Fang K, He X, Xu H, Hu Y (2020)
Bioorg Chem
99 :103888