| Title : Lipase-catalyzed kinetic resolution of 2,3-epoxy-1-tridecanol and its application to facile synthesis of (+)-disparlure - Fukusaki_1999_J.Biosci.Bioeng_87_103 |
| Author(s) : Fukusaki E , Satoda S , Senda S , Omata T |
| Ref : J Biosci Bioeng , 87 :103 , 1999 |
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Abstract :
Acylation of (+/-)-2,3-epoxy-1-tridecanol with acetic anhydride in diisopropyl ether by porcine pancreatic lipase yielded (2R, 3S)-2,3-epoxy-1-tridecanol as the remaining substrate with an optical purity of over 99% ee. (+)-Disparlure was synthesized in two steps from this optically active epoxy alcohol. |
| PubMedSearch : Fukusaki_1999_J.Biosci.Bioeng_87_103 |
| PubMedID: 16232433 |
Fukusaki E, Satoda S, Senda S, Omata T (1999)
Lipase-catalyzed kinetic resolution of 2,3-epoxy-1-tridecanol and its application to facile synthesis of (+)-disparlure
J Biosci Bioeng
87 :103
Fukusaki E, Satoda S, Senda S, Omata T (1999)
J Biosci Bioeng
87 :103