| Title : Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru - Galarza_2014_Genome.Announc_2_e00089 |
| Author(s) : Galarza M , Tarazona D , Borda V , Agapito JC , Guio H |
| Ref : Genome Announc , 2 : , 2014 |
|
Abstract :
We report the genome sequence of Mycobacterium tuberculosis INS-MDR from Peru, a multidrug-resistant tuberculosis (MDR-TB) and Latin American-Mediterranean (LAM) lineage strain. Our analysis showed mutations related to drug resistance in the rpoB (D516V), katG (S315T), kasA (G269S), and pncA (Q10R) genes. Our evidence suggests that INS-MDR may be a clonal expansion related to the African strain KZN 1435. |
| PubMedSearch : Galarza_2014_Genome.Announc_2_e00089 |
| PubMedID: 24578270 |
| Gene_locus related to this paper: myctu-RV1215C |
| Gene_locus | myctu-RV1215C |
Galarza M, Tarazona D, Borda V, Agapito JC, Guio H (2014)
Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru
Genome Announc
2 :
Galarza M, Tarazona D, Borda V, Agapito JC, Guio H (2014)
Genome Announc
2 :