| Title : Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease - Geula_1989_Brain.Res_498_185 |
| Author(s) : Geula C , Mesulam MM |
| Ref : Brain Research , 498 :185 , 1989 |
|
Abstract :
Selective cholinesterase inhibitors such as BW284C51 and iso-OMPA showed that the plaques and tangles of Alzheimer's disease contain acetylcholinesterase and butyrylcholinesterase activity. In comparison to the cholinesterases of the normal brain, the plaque and tangle-bound cholinesterases in Alzheimer's disease display major shifts in optimum pH and inhibitor sensitivity. |
| PubMedSearch : Geula_1989_Brain.Res_498_185 |
| PubMedID: 2790472 |
Geula C, Mesulam MM (1989)
Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease
Brain Research
498 :185
Geula C, Mesulam MM (1989)
Brain Research
498 :185