| Title : [Sites of synthesis of acetylcholine receptors in denervated muscles] - Giacobini_1980_Bull.Assoc.Anat.(Nancy)_64_387 |
| Author(s) : Giacobini Robecchi MG , Garelli M , Filogamo G |
| Ref : Bull Assoc Anat (Nancy) , 64 :387 , 1980 |
|
Abstract :
Muscle fibres binding with 125I alpha-bungarotoxine from Bungarus Multicinctus, after treatment with saponine, shows (in electron microscope autoradiography) intracellular binding sites identifying sites of acetylcholine receptor synthesis. In innervated muscle, the acetylcholine receptor is located only at the neuromuscular junction. In denervated muscle the receptor is distributed along the whole sarcolemma; in this situation the acetylcholine receptor is synthesized "ex novo" in the membrane system over the whole length of the muscle fibre. |
| PubMedSearch : Giacobini_1980_Bull.Assoc.Anat.(Nancy)_64_387 |
| PubMedID: 7214035 |
Giacobini Robecchi MG, Garelli M, Filogamo G (1980)
[Sites of synthesis of acetylcholine receptors in denervated muscles]
Bull Assoc Anat (Nancy)
64 :387
Giacobini Robecchi MG, Garelli M, Filogamo G (1980)
Bull Assoc Anat (Nancy)
64 :387