Godson_1999_Pest.Sci_55_189

Applying pesticides in mixture can bring about an increased level of performance which can be of benefit to manufacturers who make use of this phenomenon when formulating products. The interactions that occur can also bring about adverse effects on performance and possibly on the safety of the product to users, consumers and the environment. Because of this a product containing a mixture of active substances must be considered by registration authorities. Each discipline in the regulatory process must consider the likelihood of an interaction occurring and, as a result, request and examine the necessary data to support approval for that mixed product. Within the European Community the requirements are laid down in Directives that have been introduced to harmonise the regulatory process across Member States. The requirements of these Directives are described as an example of the regulatory process.