Griffin_2008_Glia_56_1518

Reference

Title : Biology and pathology of nonmyelinating Schwann cells - Griffin_2008_Glia_56_1518
Author(s) : Griffin JW , Thompson WJ
Ref : Glia , 56 :1518 , 2008
Abstract :

The CNS contains relatively few unmyelinated nerve fibers, and thus benefits from the advantages that are conferred by myelination, including faster conduction velocities, lower energy consumption for impulse transmission, and greater stability of point-to-point connectivity. In the PNS many fibers or regions of fibers the Schwann do not form myelin. Examples include C fibers nociceptors, postganglionic sympathetic fibers, and the Schwann cells associated with motor nerve terminals at neuromuscular junctions. These examples retain a degree of plasticity and a capacity to sprout collaterally that is unusual in myelinated fibers. Nonmyelin-forming Schwann cells, including those associated with uninjured fibers, have the capacity to act as the "first responders" to injury or disease in their neighborhoods.

PubMedSearch : Griffin_2008_Glia_56_1518
PubMedID: 18803315

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Citations formats

Griffin JW, Thompson WJ (2008)
Biology and pathology of nonmyelinating Schwann cells
Glia 56 :1518

Griffin JW, Thompson WJ (2008)
Glia 56 :1518