Title : Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4 - Hamdani_2014_Cardiovasc.Res_104_423 |
Author(s) : Hamdani N , Hervent AS , Vandekerckhove L , Matheeussen V , Demolder M , Baerts L , De Meester I , Linke WA , Paulus WJ , De Keulenaer GW |
Ref : Cardiovascular Research , 104 :423 , 2014 |
Abstract :
AIMS: Obesity and Type 2 diabetes mellitus (DM) induce left ventricular (LV) diastolic dysfunction, which contributes to an increasing prevalence of heart failure with a preserved LV ejection fraction. We investigated the effects of sitagliptin (SITA), an inhibitor of dipeptidylpeptidase-4 (DPP-4) and anti-diabetic drug, on LV structure and function of obese mice with Type 2 DM. METHODS AND |
PubMedSearch : Hamdani_2014_Cardiovasc.Res_104_423 |
PubMedID: 25341892 |
Hamdani N, Hervent AS, Vandekerckhove L, Matheeussen V, Demolder M, Baerts L, De Meester I, Linke WA, Paulus WJ, De Keulenaer GW (2014)
Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4
Cardiovascular Research
104 :423
Hamdani N, Hervent AS, Vandekerckhove L, Matheeussen V, Demolder M, Baerts L, De Meester I, Linke WA, Paulus WJ, De Keulenaer GW (2014)
Cardiovascular Research
104 :423