Title : Molluscicidal activity and mechanism of toxicity of a novel salicylanilide ester derivative against Biomphalaria species - He_2017_Parasit.Vectors_10_383 |
Author(s) : He P , Wang W , Sanogo B , Zeng X , Sun X , Lv Z , Yuan D , Duan L , Wu Z |
Ref : Parasit Vectors , 10 :383 , 2017 |
Abstract :
BACKGROUND: Schistosomiasis mansoni is one of the most important, but often neglected, tropical diseases transmitted by snails of the genus Biomphalaria. Control of the intermediate host snail plays a crucial role in preventing the spread of schistosomiasis. However, there is only one molluscicide, niclosamide, recommended by the World Health Organization. Niclosamide has been used for several decades but is toxic to non-target organisms. Therefore, it is necessary to optimize the scaffold of niclosamide and develop novel molluscicides with enhanced potency and decreased toxicity to non-target organisms. |
PubMedSearch : He_2017_Parasit.Vectors_10_383 |
PubMedID: 28793917 |
He P, Wang W, Sanogo B, Zeng X, Sun X, Lv Z, Yuan D, Duan L, Wu Z (2017)
Molluscicidal activity and mechanism of toxicity of a novel salicylanilide ester derivative against Biomphalaria species
Parasit Vectors
10 :383
He P, Wang W, Sanogo B, Zeng X, Sun X, Lv Z, Yuan D, Duan L, Wu Z (2017)
Parasit Vectors
10 :383