| Title : Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness - Henderson_2001_Toxicol.Ind.Health_17_294 |
| Author(s) : Henderson RF , Barr EB , Blackwell WB , Clark CR , Conn CA , Kalra R , March TH , Sopori ML , Tesfaigzi Y , Menache MG , Mash DC , Dokladny K , Kozak W , Kozak A , Wachulec M , Rudolph K , Kluger MJ , Singh SP , Razani-Boroujerdi S , Langley RJ |
| Ref : Toxicol Ind Health , 17 :294 , 2001 |
|
Abstract :
Subclinical, repeated exposures of F344 rats to sarin resulted in brain alterations in densities of chlonergic receptor subtypes that may be associated with memory loss and cognitive dysfunction. The exposures also depressed the immune system. The rat appears to be a good model for studying the effects of subclinical exposure to a nerve gas. |
| PubMedSearch : Henderson_2001_Toxicol.Ind.Health_17_294 |
| PubMedID: 12539875 |
Henderson RF, Barr EB, Blackwell WB, Clark CR, Conn CA, Kalra R, March TH, Sopori ML, Tesfaigzi Y, Menache MG, Mash DC, Dokladny K, Kozak W, Kozak A, Wachulec M, Rudolph K, Kluger MJ, Singh SP, Razani-Boroujerdi S, Langley RJ (2001)
Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness
Toxicol Ind Health
17 :294
Henderson RF, Barr EB, Blackwell WB, Clark CR, Conn CA, Kalra R, March TH, Sopori ML, Tesfaigzi Y, Menache MG, Mash DC, Dokladny K, Kozak W, Kozak A, Wachulec M, Rudolph K, Kluger MJ, Singh SP, Razani-Boroujerdi S, Langley RJ (2001)
Toxicol Ind Health
17 :294