Title : The ratio of acetylcholinesterase to butyrylcholinesterase influences the specificity of assays for each enzyme in human brain - Huff_1989_J.Neural.Transm_75_129 |
Author(s) : Huff FJ , Reiter CT , Rand JB |
Ref : J Neural Transm , 75 :129 , 1989 |
Abstract :
A single-vial extraction radiometric assay was used to measure acetylcholinesterase and butyrylcholinesterase in human post-mortem brain tissue. Data are presented regarding the differential inhibition of acetylcholinesterase and butyrylcholinesterase in several brain areas from a case of Alzheimer's disease and a case without neuropsychiatric disease. The results indicate that neither enzyme is entirely specific for its substrate, and the necessity for using inhibitors depends upon the ratio of acetylcholinesterase to butyrylcholinesterase in a particular sample. |
PubMedSearch : Huff_1989_J.Neural.Transm_75_129 |
PubMedID: 2918305 |
Huff FJ, Reiter CT, Rand JB (1989)
The ratio of acetylcholinesterase to butyrylcholinesterase influences the specificity of assays for each enzyme in human brain
J Neural Transm
75 :129
Huff FJ, Reiter CT, Rand JB (1989)
J Neural Transm
75 :129