Title : Effects of salsolinol, a tetrahydroisoquinolone alkaloid, on multiple schedule performance in rats - Hymowitz_1978_Pharmacol.Biochem.Behav_8_203 |
Author(s) : Hymowitz N , Brezenoff HE |
Ref : Pharmacol Biochem Behav , 8 :203 , 1978 |
Abstract :
Rats were trained to lever press under a multiple fixed-ratio fixed-interval schedule of food reinforcement. Intracerebroventricular injections of salsolinol (1-methyl-6,7-dihydroxytetrahydroisoquinoline), a condensation product of dopamine and acetaldehyde, caused a dose-related decrease in fixed-ratio responding over a dosage range of 15-120 microgram. In contrast, fixed-interval responding was only reduced at the 120 microgram dose and was increased in two of the animals after injection of 15-30 microgram of salsolinol. |
PubMedSearch : Hymowitz_1978_Pharmacol.Biochem.Behav_8_203 |
PubMedID: 652829 |
Hymowitz N, Brezenoff HE (1978)
Effects of salsolinol, a tetrahydroisoquinolone alkaloid, on multiple schedule performance in rats
Pharmacol Biochem Behav
8 :203
Hymowitz N, Brezenoff HE (1978)
Pharmacol Biochem Behav
8 :203