| Title : Cholinergic neurons with monoamine oxidase type B (MAOB)-activity in the laterodorsal tegmental nucleus of the mouse - Ikemoto_1999_Neurosci.Lett_271_53 |
| Author(s) : Ikemoto K , Kitahama K , Maeda T , Jouvet M , Nagatsu I |
| Ref : Neuroscience Letters , 271 :53 , 1999 |
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Abstract :
No neurons in the laterodorsal tegmental nucleus (LDTg) show monoamine oxidase (MAO) activity in the rat or monkey. However, in our recent study, many LDTg neurons with MAO type B (MAOB)-activity were found in MAOA-deficient mice that were derived from C3H mouse line. In the present study, LDTg neurons with MAOB-activity were found not only in normal C3H mouse but also in BALB/C and C57BL/6 mouse lines: MAO histochemistry revealed LDTg neurons with MAO-activity even after pharmacological suppression of MAOA-activity with clorgyline, a specific MAOA inhibitor, but not after pharmacological suppression of MAOB-activity with deprenyl, a specific MAOB inhibitor. LDTg neurons with MAOB-activity also showed NADPH-diaphorase-activity, a marker of cholinergic neurons. |
| PubMedSearch : Ikemoto_1999_Neurosci.Lett_271_53 |
| PubMedID: 10471212 |
Ikemoto K, Kitahama K, Maeda T, Jouvet M, Nagatsu I (1999)
Cholinergic neurons with monoamine oxidase type B (MAOB)-activity in the laterodorsal tegmental nucleus of the mouse
Neuroscience Letters
271 :53
Ikemoto K, Kitahama K, Maeda T, Jouvet M, Nagatsu I (1999)
Neuroscience Letters
271 :53