Ionov_1979_Mol.Biol_13_854

In the paper the analysis of the possible kinetic schemes is performed for the process of the combined inhibition of cholinesterases. It is shown that the considered schemes result in the identical experimental dependencies of the inhibition constants from the concentration of the inhibitor. Based on the analysis of about 200 experiments a linear dependence was found between logarithms of constants describing the reversible and irreversible action of the inhibitor.