Title : Is the acetylcholine releasing protein mediatophore present in rat brain? - Israel_1988_FEBS.Lett_233_421 |
Author(s) : Israel M , Lesbats B , Morel Ni , Manaranche R , Le Gal la Salle G |
Ref : FEBS Letters , 233 :421 , 1988 |
Abstract :
Mediatophore is a protein purified from the nerve terminal membranes of Torpedo electric organ. It confers to artificial membranes a calcium-dependent mechanism that translocates acetylcholine. When similar reconstitution experiments are applied to rat brain synaptosomal membranes they reveal the presence of mediatophore activity with properties close to those described for the Torpedo protein (extractability, sensitivity to calcium, and effect of the drug cetiedil). The activity was more abundant in synaptosomal membranes than in mitochondrial or myelinic membranes and in cholinergic areas as compared to cerebellum. |
PubMedSearch : Israel_1988_FEBS.Lett_233_421 |
PubMedID: 3384100 |
Israel M, Lesbats B, Morel Ni, Manaranche R, Le Gal la Salle G (1988)
Is the acetylcholine releasing protein mediatophore present in rat brain?
FEBS Letters
233 :421
Israel M, Lesbats B, Morel Ni, Manaranche R, Le Gal la Salle G (1988)
FEBS Letters
233 :421