| Title : Binding constants for tetramethylammonium ion determined with irreversible inhibitors of acetylcholinesterase - Iverson_1976_Can.J.Biochem_54_918 |
| Author(s) : Iverson F |
| Ref : Canadian Journal of Biochemistry , 54 :918 , 1976 |
|
Abstract :
The reversible binding constant (Ki) for tetramethylammonium ion (TMA) was determined from the decrease in the bimolecular rate constant (ki) observed with each of 21 organophosphate or carbamate inhibitors of acetylcholinesterase (EC 3.1.1.7). The Ki values obtained were reasonably constant (5.8 X 10(-4) +/- 0.38 M), and this is consistent with reports indicating that TMA binds to a single site on the enzyme. |
| PubMedSearch : Iverson_1976_Can.J.Biochem_54_918 |
| PubMedID: 990993 |
| Inhibitor | Tetramethylammonium |
Iverson F (1976)
Binding constants for tetramethylammonium ion determined with irreversible inhibitors of acetylcholinesterase
Canadian Journal of Biochemistry
54 :918
Iverson F (1976)
Canadian Journal of Biochemistry
54 :918