| Title : Regulation of acetylcholine synthesis: does cytoplasmic acetylcholine control high affinity choline uptake? - Jenden_1976_Science_194_635 |
| Author(s) : Jenden DJ , Jope RS , Weiler MH |
| Ref : Science , 194 :635 , 1976 |
|
Abstract :
When brain synaptosomes are obtained from animals that have been injected intravenously with [2H4]choline 1 minute before being killed, their high affinity [3H] choline uptake is correlated inversely with their acetylcholine content and directly with the rate at which they synthesize [2H4]acetylcholine. The control of such choline uptake by the cytoplasmic acetylcholine concentration is proposed as a mechanism regulating acetylcholine synthesis in cholinergic nerve terminals. |
| PubMedSearch : Jenden_1976_Science_194_635 |
| PubMedID: 982031 |
Jenden DJ, Jope RS, Weiler MH (1976)
Regulation of acetylcholine synthesis: does cytoplasmic acetylcholine control high affinity choline uptake?
Science
194 :635
Jenden DJ, Jope RS, Weiler MH (1976)
Science
194 :635