| Title : Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla - Jiang_2015_Nat.Prod.Res_29_842 |
| Author(s) : Jiang WW , Su J , Wu XD , He J , Peng LY , Cheng X , Zhao QS |
| Ref : Nat Prod Res , 29 :842 , 2015 |
|
Abstract :
Geissoschizine methyl ether N-oxide, a new oxindole alkaloid, along with 14 known alkaloids, was isolated from the aerial part of Uncaria rhynchophylla. Their structures were identified by comprehensive spectral methods, including 2D NMR experiments, and confirmed by comparing with the literature data. In vitro acetylcholinesterase (AChE) inhibitory activity assay showed that the new compound exhibited anti-AChE activity with IC(5)(0) value of 23.4 muM. |
| PubMedSearch : Jiang_2015_Nat.Prod.Res_29_842 |
| PubMedID: 25496282 |
Jiang WW, Su J, Wu XD, He J, Peng LY, Cheng X, Zhao QS (2015)
Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla
Nat Prod Res
29 :842
Jiang WW, Su J, Wu XD, He J, Peng LY, Cheng X, Zhao QS (2015)
Nat Prod Res
29 :842