Title : Motor end-plates in regenerating rat skeletal muscle exposed to botulinum toxin - Jirmanova_1976_Neurosci_1_345 |
Author(s) : Jirmanova I , Thesleff S |
Ref : Neuroscience , 1 :345 , 1976 |
Abstract :
Botulinum toxin type A, when applied to the extensor digitorum longus muscle of rats, reduces spontaneous and evoked transmitter release to a few per cent of the normal level. The toxin, however, fails to affect the morphological redifferentiation of the postsynaptic part of the neuromuscular junction following muscle degeneration-regeneration induced by a selective myotoxic agent, bupivacaine. This indicates that neither transmitter release nor resulting muscle activity are necessary for the differentiation of the sole plate. |
PubMedSearch : Jirmanova_1976_Neurosci_1_345 |
PubMedID: 11370519 |
Jirmanova I, Thesleff S (1976)
Motor end-plates in regenerating rat skeletal muscle exposed to botulinum toxin
Neuroscience
1 :345
Jirmanova I, Thesleff S (1976)
Neuroscience
1 :345