Title : Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats - John_2015_Pharmacogn.Mag_11_327 |
Author(s) : John J , Nampoothiri M , Kumar N , Mudgal J , Nampurath GK , Chamallamudi MR |
Ref : Pharmacogn Mag , 11 :327 , 2015 |
Abstract :
BACKGROUND: Sesame oil from the seeds of Sesamum indicum Linn. (Pedaliaceae) has been used traditionally in Indian medical practice of Ayurveda in the treatment of central nervous system disorders and insomnia. A few published reports favor the anti-dementia effect of sesamol (SML), an active constituent of sesame oil. OBJECTIVE: Thus, the present study was aimed to explore the anti-dementia effect and possible mechanism (s) of SML in aluminium chloride (AlCl3)-induced cognitive dysfunction model in rodents with special emphasis on memory centers viz., hippocampus and frontal cortex. |
PubMedSearch : John_2015_Pharmacogn.Mag_11_327 |
PubMedID: 25829772 |
John J, Nampoothiri M, Kumar N, Mudgal J, Nampurath GK, Chamallamudi MR (2015)
Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats
Pharmacogn Mag
11 :327
John J, Nampoothiri M, Kumar N, Mudgal J, Nampurath GK, Chamallamudi MR (2015)
Pharmacogn Mag
11 :327