| Title : Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships - Kang_2001_J.Nat.Prod_64_683 |
| Author(s) : Kang SY , Lee KY , Sung SH , Park MJ , Kim YC |
| Ref : Journal of Natural Products , 64 :683 , 2001 |
|
Abstract :
Acetylcholinesterase (AChE) inhibitory activity-guided fractionation of Angelica gigas led to isolation and identification of a new coumarin, peucedanone (12), and isolation of 11 known coumarins. Among them, decursinol (1) represented the highest inhibitory activity toward AChE in vitro. The correlation of the inhibitory activities of the coumarins toward AChE with their chemical structures was studied. |
| PubMedSearch : Kang_2001_J.Nat.Prod_64_683 |
| PubMedID: 11374978 |
Kang SY, Lee KY, Sung SH, Park MJ, Kim YC (2001)
Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships
Journal of Natural Products
64 :683
Kang SY, Lee KY, Sung SH, Park MJ, Kim YC (2001)
Journal of Natural Products
64 :683