Karczmar_2014_J.Mol.Neurosci_53_291

Macromolecular cholinergic pathways are involved in the regulation of addiction, emotions, and motivations, as described at this ISCM. Indeed, in view of the omnipresence in the brain of cholinergic pathways and of their connections with other transmitters' sites and pathways, their involvement in all known human and animal behaviors could be expected and numerous current reports describe such cholinergic correlates. This minireview describes the current status and the future of the cholinergic impact on behavior and emotions, and particularly on one important human phenomenon, the "self" or the "I" (it is only speculative to impute the self to animals).