| Title : Fluorogenic chemical tools to shed light on CES1-mediated adverse drug interactions - Karns_2024_Chem.Commun.(Camb)__ |
| Author(s) : Karns CJ , Spidle TP , Adusah E , Gao M , Nehls JE , Beck MW |
| Ref : Chem Commun (Camb) , : , 2024 |
|
Abstract :
Studying factors that cause interindividual variability of carboxylesterase 1 (CES1) activity is currently difficult due to limited methods. Here, fluorogenic tools for measuring CES1 activity are developed and demonstrated to report on these factors in living cells. These tools enable experiments that will develop a deeper understanding of CES1 metabolism. |
| PubMedSearch : Karns_2024_Chem.Commun.(Camb)__ |
| PubMedID: 39279555 |
Karns CJ, Spidle TP, Adusah E, Gao M, Nehls JE, Beck MW (2024)
Fluorogenic chemical tools to shed light on CES1-mediated adverse drug interactions
Chem Commun (Camb)
:
Karns CJ, Spidle TP, Adusah E, Gao M, Nehls JE, Beck MW (2024)
Chem Commun (Camb)
: