Title : Efficient preparation of optically active ketoprofen by Mucor javanicus lipase immobilized on an inorganic support - Kato_2000_J.Biosci.Bioeng_90_332 |
Author(s) : Kato K , Gong Y , Saito T , Kimoto H |
Ref : J Biosci Bioeng , 90 :332 , 2000 |
Abstract :
Lipase M from Mucor javanicus, one of nine commercially available hydrolytic enzymes, showed good enantioselectivity (E=50) for racemic ketoprofen trifluoroethyl ester in phosphate buffer (pH 7.0) containing 30% acetone. Lipase M immobilized on Toyonite 200-A showed the best selectivity (E=55) and reactivity. Moreover, the lipase could be recycled at least 5 times. |
PubMedSearch : Kato_2000_J.Biosci.Bioeng_90_332 |
PubMedID: 16232865 |
Kato K, Gong Y, Saito T, Kimoto H (2000)
Efficient preparation of optically active ketoprofen by Mucor javanicus lipase immobilized on an inorganic support
J Biosci Bioeng
90 :332
Kato K, Gong Y, Saito T, Kimoto H (2000)
J Biosci Bioeng
90 :332