| Title : Biodegradation of aromatic compounds: an overview of meta-fission product hydrolases - Khajamohiddin_2008_Crit.Rev.Microbiol_34_13 |
| Author(s) : Khajamohiddin S , Repalle ER , Pinjari AB , Merrick M , Siddavattam D |
| Ref : Crit Rev Microbiol , 34 :13 , 2008 |
|
Abstract :
Meta fission product (MFP) hydrolases catalyze hydrolysis of a low reactive carbon-carbon bond found in meta-fission products, generated during biodegradation of various aromatic compounds. These enzymes belong to the alpha/beta hydrolase super family and show structural conservation despite having poor sequence similarity. MFP-hydrolases are substrate specific and studies have indicated that this substrate specificity plays a key role in the determination of the organism's ability to degrade a particular substrate. In this concise review of MFP-hydrolases we discuss their classification, biochemical properties, the molecular basis of their substrate specificity, their catalytic mechanism, and evolutionary significance. |
| PubMedSearch : Khajamohiddin_2008_Crit.Rev.Microbiol_34_13 |
| PubMedID: 18259978 |
Khajamohiddin S, Repalle ER, Pinjari AB, Merrick M, Siddavattam D (2008)
Biodegradation of aromatic compounds: an overview of meta-fission product hydrolases
Crit Rev Microbiol
34 :13
Khajamohiddin S, Repalle ER, Pinjari AB, Merrick M, Siddavattam D (2008)
Crit Rev Microbiol
34 :13