Title : Rare and common variants in LPL and APOA5 in Thai subjects with severe hypertriglyceridemia: A resequencing approach - Khovidhunkit_2016_J.Clin.Lipidol_10_505 |
Author(s) : Khovidhunkit W , Charoen S , Kiateprungvej A , Chartyingcharoen P , Muanpetch S , Plengpanich W |
Ref : J Clin Lipidol , 10 :505 , 2016 |
Abstract :
BACKGROUND: Severe hypertriglyceridemia usually results from a combination of genetic and environmental factors. Few data exist on the genetics of severe hypertriglyceridemia in Asian populations. OBJECTIVE: To examine the genetic variants of 3 candidate genes known to influence triglyceride metabolism, LPL, APOC2, and APOA5, which encode lipoprotein lipase, apolipoprotein C-II, and apolipoprotein A-V, respectively, in a large group of Thai subjects with severe hypertriglyceridemia. |
PubMedSearch : Khovidhunkit_2016_J.Clin.Lipidol_10_505 |
PubMedID: 27206937 |
Gene_locus related to this paper: human-LPL |
Mutation | D308GfsX3_human-LPL R270G_human-LPL L279V_human-LPL R432T_human-LPL L279R_human-LPL A98T_human-LPL |
Gene_locus | human-LPL |
Disease | Hyperlipoproteinemia TypeI |
Khovidhunkit W, Charoen S, Kiateprungvej A, Chartyingcharoen P, Muanpetch S, Plengpanich W (2016)
Rare and common variants in LPL and APOA5 in Thai subjects with severe hypertriglyceridemia: A resequencing approach
J Clin Lipidol
10 :505
Khovidhunkit W, Charoen S, Kiateprungvej A, Chartyingcharoen P, Muanpetch S, Plengpanich W (2016)
J Clin Lipidol
10 :505