| Title : [Therapeutic and preventive effectiveness of zyxorin during poisoning with anticholineesterase pesticides]. [Russian] - Kokshareva_1987_Farmakol.Toksikol_50_97 |
| Author(s) : Kokshareva NV , Kagan Iu S , Ovsiannikova LM , Seberini S , Ungvari D |
| Ref : Farmakologiia i Toksikologiia , 50 :97 , 1987 |
|
Abstract :
Zyxorin (50-100 mg/kg) was found to produce a significant increase of the content (activity) of components of electron transport microsomal circuit and is similar to phenobarbital by its inducing effect. At preventive and therapeutic-preventive administration it enhances resistance of albino rats to anticholinesterase pesticides (actellis, valexon, 0,0-dimethyl-0-2,2-dichlorvinylphosphate, clorofos, hostaquick, dioxycarb, primor, sevine, furadan), prevents the development of neuromuscular blockade. The introduction of zyxorin into a complex therapy with specific agents (atropine, reactivators of cholinesterase) potentiates their antidotic effect at poisoning with DDVP. |
| PubMedSearch : Kokshareva_1987_Farmakol.Toksikol_50_97 |
| PubMedID: 3436439 |
Kokshareva NV, Kagan Iu S, Ovsiannikova LM, Seberini S, Ungvari D (1987)
[Therapeutic and preventive effectiveness of zyxorin during poisoning with anticholineesterase pesticides]. [Russian]
Farmakologiia i Toksikologiia
50 :97
Kokshareva NV, Kagan Iu S, Ovsiannikova LM, Seberini S, Ungvari D (1987)
Farmakologiia i Toksikologiia
50 :97