| Title : Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation - Kuno_1996_J.Antibiotics_49_748 |
| Author(s) : Kuno F , Shiomi K , Otoguro K , Sunazuka T , Omura S |
| Ref : Journal of Antibiotics , 49 :748 , 1996 |
|
Abstract :
The structures of new acetylcholinesterase inhibitors, arisugacins A and B, were elucidated by NMR study. Arisugacins have a (4aR,6aR,12aS,12bS)-4a,6,6a,12,12a, 12b-hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4H,11H -naphtho[2,1-b] pyrano[3,4-e]pyran-1,11(5H)-dione moiety in common and 3,4-dimethoxyphenyl or 4-methoxyphenyl residues are attached to C-9 of the moiety. |
| PubMedSearch : Kuno_1996_J.Antibiotics_49_748 |
| PubMedID: 8823505 |
| Inhibitor | ArisugacinA ArisugacinB |
Kuno F, Shiomi K, Otoguro K, Sunazuka T, Omura S (1996)
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation
Journal of Antibiotics
49 :748
Kuno F, Shiomi K, Otoguro K, Sunazuka T, Omura S (1996)
Journal of Antibiotics
49 :748