| Title : A novel skeleton alkaloid from Portulaca oleracea L. and its bioactivities - Lan_2023_Fitoterapia__105608 |
| Author(s) : Lan X , Guo S , Zhao Y , Zhang M , Zhang D , Leng A , Ying X |
| Ref : Fitoterapia , :105608 , 2023 |
|
Abstract :
A novel skeleton alkaloid was obtained from Portulaca oleracea L., which was identified as 10,11-dihydroxybenzo[5',6'] pentaleno[1',2':3,4]pyrrolo[2,1-b]oxazol-7(11bH)-one, named oleracone M, and its structure was determined using UHPLC-ESI-QTOF/MS, 1D NMR and 2D NMR spectroscopy, and circular dichroism. Then the bioactivities of the compound were investigated including the anti-inflammatory, anti-acetylcholinesterase and antioxidant activities. The results showed that the novel skeleton alkaloid exhibited the potent effect on inhibiting the secretion of IL-1beta at 10 microM, anticholinesterase activity with IC(50) value of 49.58 microM, and antioxidant activity with IC(50) value of 66.43 microM. |
| PubMedSearch : Lan_2023_Fitoterapia__105608 |
| PubMedID: 37453700 |
Lan X, Guo S, Zhao Y, Zhang M, Zhang D, Leng A, Ying X (2023)
A novel skeleton alkaloid from Portulaca oleracea L. and its bioactivities
Fitoterapia
:105608
Lan X, Guo S, Zhao Y, Zhang M, Zhang D, Leng A, Ying X (2023)
Fitoterapia
:105608