| Title : Flexible Total Synthesis of 11-Deoxylandomycins and Their Non-Natural Analogues by Way of Asymmetric Metal Catalysis - Lee_2020_Angew.Chem.Int.Ed.Engl_59_2349 |
| Author(s) : Lee J , Kang J , Lee S , Rhee YH |
| Ref : Angew Chem Int Ed Engl , 59 :2349 , 2020 |
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Abstract :
A de novo first collective total synthesis of 11-deoxylandomycins is reported. A signature step is featured by the Pd-catalyzed asymmetric addition of alcohol to ene-alkoxyallenes that assembles oligomeric 2,3,6-trideoxyoligosaccharides. The unique feature of the protocol is illustrated by a flexible access to various natural 11-deoxylandomycins as well as non-natural analogues. |
| PubMedSearch : Lee_2020_Angew.Chem.Int.Ed.Engl_59_2349 |
| PubMedID: 31737974 |
| Gene_locus related to this paper: aspa1-anee |
| Gene_locus | aspa1-anee |
Lee J, Kang J, Lee S, Rhee YH (2020)
Flexible Total Synthesis of 11-Deoxylandomycins and Their Non-Natural Analogues by Way of Asymmetric Metal Catalysis
Angew Chem Int Ed Engl
59 :2349
Lee J, Kang J, Lee S, Rhee YH (2020)
Angew Chem Int Ed Engl
59 :2349