| Title : Novel Isochroman Dimers from Stachybotrys sp. PH30583: Fermentation, Isolation, Structural Elucidation and Biological Activities - Li_2017_Planta.Med_83_654 |
| Author(s) : Li W , Yang YB , Yang XQ , Xie HD , Shao ZH , Zhou H , Miao CP , Zhao LX , Ding ZT |
| Ref : Planta Med , 83 :654 , 2017 |
|
Abstract :
The rare anishidiol and five new isochromans, including three novel dimers with unprecedented skeletons, were isolated from Stachybotrys sp. PH30583. Their structures were determined by spectral analyses. The bioactivities of these compounds were also investigated. The dimers (6-10) inhibited acetylcholinesterase at 50 microM, but the monomers did not. To investigate the biogenesis of the novel dimers, a time-course investigation of metabolite production was undertaken. |
| PubMedSearch : Li_2017_Planta.Med_83_654 |
| PubMedID: 27806408 |
Li W, Yang YB, Yang XQ, Xie HD, Shao ZH, Zhou H, Miao CP, Zhao LX, Ding ZT (2017)
Novel Isochroman Dimers from Stachybotrys sp. PH30583: Fermentation, Isolation, Structural Elucidation and Biological Activities
Planta Med
83 :654
Li W, Yang YB, Yang XQ, Xie HD, Shao ZH, Zhou H, Miao CP, Zhao LX, Ding ZT (2017)
Planta Med
83 :654