| Title : Structurally diverse terpenoids from Elephantopus scaber L. and their acetylcholinesterase inhibitory activities - Li_2023_Phytochemistry__113892 |
| Author(s) : Li JY , Dong SH , Zhang X , Liu ZJ , Hao JL , Lin B , Bai M , Huang XX , Song SJ |
| Ref : Phytochemistry , :113892 , 2023 |
|
Abstract :
Three undescribed compounds elephantopuscabers A-C, along with one previously reported compound spirowallichiione, were isolated from Elephantopus scaber L. Their structures were determined via extensive NMR spectroscopic analysis, quantum chemical calculations, and single-crystal X-ray diffraction crystallography. A plausible biosynthetic pathway for spirowallichiione was proposed. All the isolated compounds were tested for their acetylcholinesterase inhibitory activities. Among them, elephantopuscaber B and C displayed promising inhibitory activities against AChE, and the binding sites were predicted by molecular docking. |
| PubMedSearch : Li_2023_Phytochemistry__113892 |
| PubMedID: 37813132 |
Li JY, Dong SH, Zhang X, Liu ZJ, Hao JL, Lin B, Bai M, Huang XX, Song SJ (2023)
Structurally diverse terpenoids from Elephantopus scaber L. and their acetylcholinesterase inhibitory activities
Phytochemistry
:113892
Li JY, Dong SH, Zhang X, Liu ZJ, Hao JL, Lin B, Bai M, Huang XX, Song SJ (2023)
Phytochemistry
:113892