| Title : Essential oil from Piper tuberculatum Jacq. (Piperaceae) and its majority compound beta-caryophyllene: mechanism of larvicidal action against Aedes aegypti (Diptera: Culicidae) and selective toxicity - Lima_2024_Environ.Sci.Pollut.Res.Int__ |
| Author(s) : Lima SC , de Oliveira AC , Tavares CPS , Costa MLL , Roque RA |
| Ref : Environ Sci Pollut Res Int , : , 2024 |
| Abstract : Synthetic insecticides have been the primary approach in controlling Aedes aegypti; however, their indiscriminate use has led to the development of resistance and toxicity to non-target animals. In contrast, essential oils (EOs) are alternatives for vector control. This study investigated the mechanism of larvicidal action of the EO and beta-caryophyllene from Piper tuberculatum against A. aegypti larvae, as well as evaluated the toxicity of both on non-target animals. The EO extracted from P. tuberculatum leaves was majority constituted of beta-caryophyllene (54.8%). Both demonstrated larvicidal activity (LC(50) of 48.61 and 57.20 ppm, p<0.05), acetylcholinesterase inhibition (IC(50) of 57.78 and 71.97 ppm), and an increase in the production of reactive oxygen and nitrogen species in larvae after exposure to the EO and beta-caryophyllene. Furthermore, EO and beta-caryophyllene demonstrate no toxicity to non-target animals Toxorhynchites haemorrhoidalis, Anisops bouvieri, and Diplonychus indicus (100% of survival rate), while the insecticide alpha-cypermethrin was highly toxic (100% of death). The results demonstrate that the EO from P. tuberculatum and beta-caryophyllene are important larvicidal agents. |
| ESTHER : Lima_2024_Environ.Sci.Pollut.Res.Int__ |
| PubMedSearch : Lima_2024_Environ.Sci.Pollut.Res.Int__ |
| PubMedID: 38684608 |
Lima SC, de Oliveira AC, Tavares CPS, Costa MLL, Roque RA (2024)
Essential oil from Piper tuberculatum Jacq. (Piperaceae) and its majority compound beta-caryophyllene: mechanism of larvicidal action against Aedes aegypti (Diptera: Culicidae) and selective toxicity
Environ Sci Pollut Res Int
:
Lima SC, de Oliveira AC, Tavares CPS, Costa MLL, Roque RA (2024)
Environ Sci Pollut Res Int
: