Little_2008_Expert.Opin.Investig.Drugs_17_209

Reference

Title : An update on huperzine A as a treatment for Alzheimer's disease - Little_2008_Expert.Opin.Investig.Drugs_17_209
Author(s) : Little JT , Walsh S , Aisen PS
Ref : Expert Opin Investig Drugs , 17 :209 , 2008
Abstract :

Huperzine A is a natural cholinesterase inhibitor derived from the Chinese herb Huperzia serrata. There is evidence that huperzine A may compare favorably in symptomatic efficacy to cholinesterase inhibitors in use. In addition, huperzine A has antioxidant and neuroprotective properties that suggest that it may be useful as a disease-modifying treatment for Alzheimer's disease (AD). The drug is available as a nutriceutical in the US. However, there have been no published controlled clinical trials outside China assessing its toxicity and efficacy. This paper reviews the development of huperzine A as a treatment for AD, including the Phase II trial now under way in the US.

PubMedSearch : Little_2008_Expert.Opin.Investig.Drugs_17_209
PubMedID: 18230054

Related information

Citations formats

Little JT, Walsh S, Aisen PS (2008)
An update on huperzine A as a treatment for Alzheimer's disease
Expert Opin Investig Drugs 17 :209

Little JT, Walsh S, Aisen PS (2008)
Expert Opin Investig Drugs 17 :209