Title : Naltrexone attenuation of conditioned but not primary reinforcement of nicotine in rats - Liu_2009_Psychopharmacology.(Berl)_202_589 |
Author(s) : Liu X , Palmatier MI , Caggiula AR , Sved AF , Donny EC , Gharib M , Booth S |
Ref : Psychopharmacology (Berl) , 202 :589 , 2009 |
Abstract :
RATIONALE: Opioid neurotransmission has been implicated in reinforcement-related processes for several drugs of abuse, including opiates, stimulants, and alcohol. However, less is known about its role in the motivational effects of nicotine and nicotine-associated environmental cues. OBJECTIVE: This study investigated whether pretreatment with naltrexone, an opioid receptor antagonist, alters conditioned incentive salience of nicotine cues under two conditions: cue-induced reinstatement of nicotine-seeking after extinction and cue-maintained responding during extinction. The effect of naltrexone on nicotine self-administration during the maintenance phase was also examined. MATERIALS AND |
PubMedSearch : Liu_2009_Psychopharmacology.(Berl)_202_589 |
PubMedID: 18807246 |
Liu X, Palmatier MI, Caggiula AR, Sved AF, Donny EC, Gharib M, Booth S (2009)
Naltrexone attenuation of conditioned but not primary reinforcement of nicotine in rats
Psychopharmacology (Berl)
202 :589
Liu X, Palmatier MI, Caggiula AR, Sved AF, Donny EC, Gharib M, Booth S (2009)
Psychopharmacology (Berl)
202 :589